Difference: ElementaryFluxModes (1 vs. 6)

Revision 62014-10-09 - TWikiAdminUser

Line: 1 to 1
 
META TOPICPARENT name="BiosysInternal.FlorianCentler"
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically

Revision 52014-10-09 - StephanRichter

Line: 1 to 1
Changed:
<
<
META TOPICPARENT name="FlorianCentler"
>
>
META TOPICPARENT name="BiosysInternal.FlorianCentler"
 
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically
  • linear superposition of elementary flux modes gives all possible steady state flux distributions
Line: 13 to 13
  -- FlorianCentler - 16 Feb 2004
Added:
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META TOPICMOVED by="StephanRichter" date="1412847658" from="Coreteam.ElementaryFluxModes" to="Biosys.ElementaryFluxModes"

Revision 42005-02-10 - FlorianCentler

Line: 1 to 1
 
META TOPICPARENT name="FlorianCentler"
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically
Line: 8 to 8
 

Organizations and Elementary Flux Modes

  • organizations tend to be larger than comparable EFMs. In EFMS, reactions can be completely shut off. Not possible for an organization.
    MOVED TO... This might become possible if enzymes are modeled as explicit molecules ( metatool2rea -e ).
Added:
>
>
  • EFM is about reactions, OT is about molecules (well, molecules always implicitely include reactions)
  • EFM is about steady state, OT is about steady state or increasing mass
  -- FlorianCentler - 16 Feb 2004

Revision 32004-02-26 - FlorianCentler

Line: 1 to 1
 
META TOPICPARENT name="FlorianCentler"
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically
  • linear superposition of elementary flux modes gives all possible steady state flux distributions
Changed:
<
<
  • metabolites are internal or external, external metabolites are "clamped" (reactions don't affect their concentrations), only internal metabolites have to fullfill the steady state condition
>
>
  • metabolites are internal or external, external metabolites are "clamped" (reactions don't affect their concentrations on the system-level), only internal metabolites have to fullfill the steady state condition (thus only external metabolites change in concentration, they can act as input and output).
 

Organizations and Elementary Flux Modes

Changed:
<
<
  • organizations tend to be larger then comparable EFMs. In EFMS, reactions can be completely shut off. Not possible for an organization.
>
>
  • organizations tend to be larger than comparable EFMs. In EFMS, reactions can be completely shut off. Not possible for an organization.
    MOVED TO... This might become possible if enzymes are modeled as explicit molecules ( metatool2rea -e ).
  -- FlorianCentler - 16 Feb 2004

Revision 22004-02-17 - FlorianCentler

Line: 1 to 1
 
META TOPICPARENT name="FlorianCentler"
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically
  • linear superposition of elementary flux modes gives all possible steady state flux distributions
Changed:
<
<
  • metabolites are internal or external, external metabolites are "clamped" (reactions don't affect their concentrations)
>
>
  • metabolites are internal or external, external metabolites are "clamped" (reactions don't affect their concentrations), only internal metabolites have to fullfill the steady state condition

Organizations and Elementary Flux Modes

  • organizations tend to be larger then comparable EFMs. In EFMS, reactions can be completely shut off. Not possible for an organization.
  -- FlorianCentler - 16 Feb 2004

Revision 12004-02-16 - FlorianCentler

Line: 1 to 1
Added:
>
>
META TOPICPARENT name="FlorianCentler"
  • flux mode : steady-state flux distribution , proportions of fluxes are fixed
  • elementary flux mode : nondecomposable flux mode, minimal set of enzymes that can operate at steady state with all irreversible reactions proceeding in the direction prescribed thermodynamically
  • linear superposition of elementary flux modes gives all possible steady state flux distributions
  • metabolites are internal or external, external metabolites are "clamped" (reactions don't affect their concentrations)

-- FlorianCentler - 16 Feb 2004

 
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